Throughout this period, the Cholas were constantly troubled by the ever resilient Sinhalas trying to overthrow the Chola occupation of Lanka, Pandya princes trying to win independence for their traditional territories, and by the growing ambitions of the Chalukyas in the western Deccan. The history of this period was one of constant warfare between the Cholas and of these antagonists. A balance of power existed between the Chalukyas and the Cholas and there was a tacit acceptance of the Tungabhadra river as the boundary between the two empires. However, the bone of contention between these two powers was the growing Chola influence in the Vengi kingdom. The Cholas and Chalukyas fought many battles and both kingdoms were exhausted by the endless battles and a stalemate existed.
Marital and political alliances between the Eastern Chalukya kings based around Vengi located on the south banks of the river Godavari began during the reign of Rajaraja following his invasion of Vengi. Virarajendra Chola's son Athirajendra Chola was assassinated in a civil disturbance in 1070 and Kulothunga Chola I ascended the Chola throne starting the Chalukya Chola dynasty. Kulothunga was a son of the Vengi king Rajaraja Narendra. The Chalukya Chola dynasty saw very capable rulers in Kulothunga Chola I and Vikrama Chola, however the eventual decline of the Chola power practically started during this period. The Cholas lost control of the island of Lanka and were driven out by the revival of Sinhala power. Around 1118 they also lost the control of Vengi to Western Chalukya king Vikramaditya VI and Gangavadi (southern Mysore districts) to the growing power of Hoysala Vishnuvardhana, a Chalukya feudatory. In the Pandya territories, the lack of a controlling central administration caused a number of claimants to the Pandya throne to cause a civil war in which the Sinhalas and the Cholas were involved by proxy. During the last century of the Chola existence, a permanent Hoysala army was stationed in Kanchipuram to protect them from the growing influence of the Pandyas. Rajendra Chola III was the last Chola king. The Kadava chieftain Kopperunchinga I even captured Rajendra and held him prisoner. At the close of Rajendra’s reign (1279), the Pandyan Empire was at the height of prosperity and had completely absorbed the Chola kingdom.